{"id":13313,"date":"2020-08-13T20:09:47","date_gmt":"2020-08-13T18:09:47","guid":{"rendered":"https:\/\/dva.com\/?p=13313"},"modified":"2020-08-13T20:15:03","modified_gmt":"2020-08-13T18:15:03","slug":"formulacion-de-tabletas","status":"publish","type":"post","link":"https:\/\/dva.com\/mx\/blog-mx\/formulacion-de-tabletas\/","title":{"rendered":"Formulaci\u00f3n de tabletas"},"content":{"rendered":"

Gran parte de los medicamentos disponibles en el mercado son tabletas, en DVA contamos con materiales espec\u00edficos y de alta especialidad que pueden ayudar a cubrir los retos de formulaci\u00f3n cotidianos que permiten obtener mejores propiedades de flujo, compresibilidad, lubricaci\u00f3n, uniformidad, cohesividad, etc., y as\u00ed optimizar los procesos productivos.<\/p>\n

DEFINICI\u00d3N<\/strong>
\nTambi\u00e9n se les conoce como comprimidos, y son una mezcla de distintos materiales tales como: az\u00facares, pol\u00edmeros, ceras, plastificantes, etc., con propiedades particulares para poder ser modificada y transformada en tabletas.<\/p>\n

Las hay de liberaci\u00f3n inmediata, prolongada, retardada, masticables, efervescentes, dispersables, etc.<\/p>\n

Los principales retos al formular tabletas son:
\n1. Principios activos (API\u00b4s) con sabores amargos, olores desagradables o sensibles al ox\u00edgeno, pueden requerir una encapsulaci\u00f3n o recubrimiento posterior a la compresi\u00f3n.
\n2. Principios activos con escasa humectabilidad, bajas propiedades de disoluci\u00f3n o gran dosificaci\u00f3n.<\/p>\n

PUNTOS IMPORTANTES A CONSIDERAR PARA FORMULAR TABLETAS<\/strong><\/p>\n

1. Suficientes propiedades cohesivas para formar tabletas firmes y fuertes.
\n2. Propiedades lubricantes para prevenir que se peguen los materiales a punzones y matrices.
\n3. Adecuado flujo de la mezcla de polvos desde la tolva al llenado uniforme de las matrices.
\n4. Uniformidad en la dosis del f\u00e1rmaco en cada tableta.
\n5. Capaz de ser procesada en m\u00e1quinas de alta producci\u00f3n.<\/p>\n

EXCIPIENTES B\u00c1SICOS PARA FORMULAR TABLETAS<\/strong>
\n\u2022 Diluentes \u2022 Aglutinantes \u2022 Desintegrantes \u2022 Lubricantes \u2022 Antiadherentes \u2022 Deslizantes
\n\u2022 Agentes humectantes o tensoactivos \u2022 Colorantes \u2022 Saborizantes \u2022 Edulcorantes<\/p>\n

DVA cuenta con un amplio y versatil portafolio de oportunidades para seleccionar el mejor excipiente para tus formulaciones. Consulta nuestro cat\u00e1logo.<\/p>\n","protected":false},"excerpt":{"rendered":"

Gran parte de los medicamentos disponibles en el mercado son tabletas, en DVA contamos con materiales espec\u00edficos y de alta […]<\/p>\n","protected":false},"author":1,"featured_media":13315,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269],"tags":[],"class_list":["post-13313","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-mx"],"yoast_head":"\nFormulaci\u00f3n de Tabletas Eficiente<\/title>\n<meta name=\"description\" content=\"Optimice la producci\u00f3n de tabletas con los materiales especializados de DVA. 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